I guess it would depend on the material itself and your situation while live. Obviously if you're playing backing tracks at a venue over a known pair of loudspeakers, you'll want to reference your mix on them and make mixing decisions based on those speakers and the acoustics of the venue if that's where your backing tracks will primarily be heard.
At the very least, make several different mixes of the backing tracks that each adhere to certain characteristics, I.E. one mix light in the bass/low end, the other a little heavier, so on and so forth... and see if you can play all of the versions through the loudspeakers at soundcheck and determine which mix works better for the specific venue.
Depending on what exactly your backing tracks are, you may not even have to worry much.
May I ask what your backing tracks consist of?
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