Nice idea, it would be great if this thread took off.
My nomination is Autolux -
Future Perfect (2004)
For me this is one of the standout indie/alternative albums of the 00's. It incorporates a lot of influences ranging from space-rock, shoegaze, post-punk, Swirlies, etc. and is such an enjoyable album to listen to from start to finish without skipping a track. This album is a great discovery for anyone.