Originally Posted by Mykonos

Tali and Miranda are the most popular ones for ManSheps, and FemSheps are more often than not romancing Garrus and Liara. It depends really. The thing you notice about the romances in Mass Effect is that they all seem to appeal to an individual's preferences. Just to name a few, Miranda's the standard ridiculously attractive femme fatale, Tali's the jailbait cutesie-pie, Liara's the awkward smart girl, Kaiden's the good-natured hunk, Thane's the troubled poet and Jack's the punky BDSM girl.