PRS, or Schecter to HD500 to (crappy) Line-6 75w through Line-6 4x10 (top stack), and early 90's Crate 4x12 (bottom stack).
My style is pretty much Metal oriented, but I can get some nice cleans and blues-ey stuff from my HD500 too. It pretty much drives my sound, but a lot of tone is in the fingers as well.
Here's an example of a BB King style I did over a BT:
SoundClick artist: PRD Ideas - page with MP3 music downloads
I've been wanting to upgrde my amp for some time now.