I can't really speak much on this. So I will speak from the perspective of musicians I've talked to, both self taught and learning by ear, apposed to non-self taught...
I feel that self taught musicians tend to be more creative, better able to improvise on the spot. Non-self taught musicians can do most everything self taught musicians can, but I really feel that non-self taught maybe have a bit of an advantage in creative areas, improvisational ability.
I am on lunch break from work so I will elaborate once I am home.
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