Zappa, the Beatles, Velvets, are the ones that immediately come to mind. Just the scope of influence they have had. Probably say the Kinks for kicking off the whole garage thing aswell.
I wouldn't know what to choose for the jazz and avant garde/experimental genres - you had Miles Davis first doing the fusion thing (or did Zappa beat him to it?) and I'm sure Stockhausen/Cage etc were pushing boundaries but I'm not sure about that particular era. Where's cardboard adolescent when ya need him?
edit: maybe the Stones, also the Yardbirds for pushing guitar solos to the fore? Must be forgetting so many....
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