If I had to choose, then possibly some of the rather sad deaths like recent Brian Delp's (Boston's old singer) recent suicide .. Badfinger is another band with a couple of suicides more or less because of troubles they had with the music industry, but it's still sort of part of their legend .. Sometimes, a legend as victims, sadly.
May they rest in peace.
I know my post sort of misses the point of the thread, though. So don't feel like you have to point it out.
Edit :
To contribute a little, I'll mention Jeff Buckley. The poor sod only lived to make his debut.