Are these all from one genre?
 

Matthew Ryan - Follow the Leader
Pete Yorn - Lose You
Joshua Radin - Closer

..and pretty much any and all songs used in Grey's Anatomy and House. Is it just Alternative? Or Indie or some new fangled genre I don't know about.

Joshua Radin = Scrubs

Yeah he was featured on there as well. Actually I watch that quite a bit and have never even watched Grey's Anatomy. Scrubs uses the same kind of music too

"Grey's Anatomy - Closer, The Fear You Won't Fall, These Photographs, Sky, One Of Those Days" from Wiki these were songs of his that were used on the show

Copying Scrubs as usual. Joshua Radin is a friend of Zach Braff, and as Braff suggests a lot of the music on the show (e.g the opening song "I'm not Superman"), he suggested mostly Radin's songs. Usually, when you have a Zach Braff movie, you should expect hearing a couple of Radin songs.

Tho I don't know about House, I never noticed these kind of songs, as the show doesn't get that emotional.

I got Follow the Leader and Lose You from House. They're both pretty emotional IMO. I've watched the show a couple times and although House may not be emotional, the show (at least to me) can be. Lose You was from the episode that the guy loses his wife and Kutner committed suicide.

I never liked House after the third season, it got a bit too Grey's anatomy for me. The songs were different on the first 3 seasons.

I guess the season 4-... of House can belong to this genre.