The only possible reason to alter the tuning is perhaps MAYBE theres an infinitesimal change in how certains notes will resonate. I can see this helpful in certain cases; my crappy stratocaster sometimes resonates on certain frets in a bad way, making my amp peak because of the big increase in certain harmonics.
Oh wait, that's probably because I have a crappy guitar. Why the hell do you want to change the tuning like this?!
Hm I suppose it may give your music a little bit of a different feel, but most people probably wouldn't ever even know unless they tried to play along and noticed that they had to tune their guitar slightly lower. Whoop-de-doo.
I think this whole thread has been over-analysed by now though.
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