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How many do I think can be at the very least improved without the use of drugs? Most, if not all of them, but I'm not really qualified to say.
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A significant improvement though? Yes, positive lifestyle chanes can definitely help, but sometimes drugs are simply needed to help along the process. It's the way you balance drugs and lifestyle changes and/or therapy to see a maximum benefit. Just considering depression and GAD, many people just don't have the proper serotonin levels to be able to cope, so SSRIs enable them to achieve the maximum benefit.
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